About Us

Yen-Ling Angelo Chiu 邱彥霖

Yen-Ling Chiu received an M.D. from National Taiwan University and a Ph.D. in immunology from Johns Hopkins University School of Medicine. He works as a physician, professor, and clinician scientist at Far Eastern Memorial Hospital, Yuan Ze University, and National Taiwan University. He enjoys biomedical engineering, working with people, traveling, and listening to music.

I-Yu Katherine Chen
陳一攸

In the center of the room, there sits I-Yu. She is the administrative head of Chiu Lab and is also the lab expert in flow cytometry and cell culture experiments. She received her MS degree in biomedical engineering from Chung Yuan Christian University. She is now working on the Immune Age Index and iESRD cohort. In her free time, she loves wine.

Kai-Hsiang Victor Shu
徐愷翔

Kai-Hsiang received his M.D. degree from National Taiwan University and is also a Ph.D. candidate at the Graduate School of Immunology of NTU. He works at FEMH as a nephrologist and loves to read scientific and clinical papers while taking care of transplantation patients. He is working on the chronic inflammation and mechanism of immunosenescence in renal failure patients.

Ruo-Wei Vivi Hung
洪若維

Vivi has great scientific curiosity and takes on the biggest project in the lab (TPMIC). She handles all the crazy stuff associated with it. Vivi is good at organizing and she creates wonderful PowerPoint slides. She is also the lab go to person for ELISA assays.

Yi-Fang Grace Chuang
莊宜芳

Professor Yi-Fang Chuang is an epidemiologist and psychiatrist. She received her M.D. degree from National Taiwan University and her epidemiology Ph.D. from Johns Hopkins University School of Public Health. She is pivotal in establishing the longitudinal aging cohort EMCIT in New Taipei City. She works as a full professor in epidemiology at National Yang Ming Chiao Tung University and as an adjunct psychiatrist at Far Eastern Memorial Hospital. She not only works closely with the Chiu Lab for dementia-related research but also assists in many statistical analyses.

Kwan-Yu Lee
李觀宇

Kwan-Yu is a MS student at the Graudate Institute of Medicine at YZU. He received his M.D. degree from Kaoshiung Medical University. Currently, he works as clinical oncologist at FEMH. He is currently trying to use EBV-specific T cells in a first-in-human clinical trial to treat nasopharyngeal carcinoma.

Yu-Hsiang Rita Huang
黃渝翔

Rita just joined the lab in 2022. She was in charge of projects regarding rapid antigen testing for COVID-19 and is now working on using stem cells to treat animal models of kidney failure in order to find a regenerative cure for patients.

Yun-Ting Juan
阮芸婷

Yun-Ting received her M.D. degree from NCCU and works in FEMH as a nephrologist. Her project is identifying a combination of biomarkers for diagnosing IgA nephropathy to avoid renal biopsy. In her free time, she is usually in Japan or enjoying family time with her boy.

Yen-Hsiang Eason Huang
黃彥翔

Eason is an excellent clinical neurologist working at FEMH. His study focuses on finding blood-based biomarkers for patients with dementia. He also partners with a start-up to utilize digital tools for early detection.

I-Mei Kristen Tseng
曾意媚

Kristen is from Vietnam. She has a cat. Currently, she works on amyloid-reactive T cells and how they promote neuroinflammation.

Bin-Rung Bruce Chuang
莊秉融

Bruce graduated from FuJen Christian University in 2024. He started to work on NK cells when he joined the lab in 2020 as a medical student, and his research was awarded a travel grant from APCN. Bruce is trying to publish his first paper on NK cell aging and dysfunction in hemodialysis patients of the iESRD cohort.

Chen-Hua Andrea Lin
林辰樺

Andrea received a master’s degree from the University of Queensland and a PhD from the Institute of Public Health at National Yang Ming Chiao Tung University. She is currently working as a postdoctoral researcher in the lab. Her research focuses on the potential mechanisms underlying cognitive decline and factors associated with brain health, with the goal of contributing to the promotion of healthy aging.

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  • 本研究為本實驗室系統性探討健康成人之年齡依賴性免疫特徵,並建立具臨床應用價值之免疫細胞參考範圍。研究結合363名台灣健康成人之原始資料,以及大規模系統性回顧與統合分析,全面解析T細胞、B細胞、自然殺手細胞(NK)及單核球等免疫子群隨年齡變化之趨勢。研究發現,隨著年齡增長,CD8⁺ T細胞與B細胞呈現下降,而CD4/CD8比例與NK細胞則顯著上升,顯示免疫老化之典型特徵;此外,初始型T細胞減少與記憶型T細胞增加的轉變亦清楚呈現。進一步分析亦揭示性別對免疫組成具有重要影響。本研究所建立之年齡與性別分層免疫參考值,可作為臨床免疫監測與精準醫療的重要基礎,對於老化相關疾病之預防與管理具有關鍵意義。 Our study represents a key achievement of our laboratory, providing a comprehensive characterization of age-dependent immune profiles in… Read more.

  • IgA 腎病變是一種典型的免疫複合體疾病。致病機制主要源於黏膜免疫系統失調(如腸道或呼吸道反覆感染),導致血中出現異常的半乳糖缺乏-IgA1(Galactose-deficient IgA1, Gd-IgA1),進而引發一連串連鎖反應造成免疫系統攻擊腎臟組織。已知除了不正常B細胞抗體產生,亦存在腸胃道與呼吸道黏膜免疫缺陷;IgAN 患者體內的 gamma-delta T 細胞亞群常呈現數量減少或分佈異常。這種黏膜免疫屏障的失常,被認為是誘發體內產生異常 IgA 的主因之一。 亞東醫院腎臟內科與台大醫院合作,團隊研究發現,IgAN 患者的血漿 C5a、factor Ba、Gd-IgA1 均顯著高於 FSGS 患者與健康對照。這表示 IgAN 中不僅有終端補體路徑活化,也有替代補體路徑活化。其中 factor… Read more.

  • Alzheimer’s disease is a dreadful disease affecting millions of people worldwide. Our lab has been fascinated by identifying peripheral immunological… Read more.